Cell Reprogramming

Curated by REGENERAR, Faculty of Medicine, University of Coimbra / CNC-UC / CIBB →

Transforming the body’s own cells into functioning neurons. Instead of replacing damaged tissue from outside, cell reprogramming works with existing non-neuronal cells — guiding them to become the neurons needed to restore brain function. This area covers epigenetic editing techniques and their potential to unlock the brain’s capacity for self-repair.

REGENERAR

Faculty of Medicine, University of Coimbra / CNC-UC / CIBB
Lead researcher: Lino Ferreira

The REGENERAR research project aims to use epigenetic tools that allow certain brain cells to be reprogrammed into neurons, manipulating cells that have increased in number after the disease process into neuronal cells important for brain function.

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Search methodology

This area is populated using the following search queries, defined by the scientific curator.

Cell Reprogramming - Neural PubMed
(cell reprogramming[Title/Abstract]) AND (brain[Title/Abstract] OR neural[Title/Abstract] OR neuron[Title/Abstract])
Epigenetic Editing - Neuroregeneration PubMed
(epigenetic editing[Title/Abstract]) AND (brain regeneration[Title/Abstract] OR neuroregeneration[Title/Abstract])
Non-Viral Delivery - CNS Reprogramming PubMed
(non-viral delivery[Title/Abstract]) AND (brain[Title/Abstract] OR CNS[Title/Abstract]) AND (reprogramming[Title/Abstract])
Direct Neuronal Reprogramming - Stroke PubMed
(direct neuronal reprogramming[Title/Abstract]) AND (ischemic[Title/Abstract] OR stroke[Title/Abstract])
In Vivo Reprogramming - Glia to Neuron PubMed
(in vivo reprogramming[Title/Abstract]) AND (astrocyte[Title/Abstract] OR glia[Title/Abstract]) AND (neuron[Title/Abstract])

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